
			Package: 5 Vials x 150 IU Usage: Injectable Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating, etc. Produced by: China



	Price: $880.00

Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online

Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)

DESCRIPTION:
Botulinum Toxin Type A is type-A toxin that has 150 IU in one vial and may be used into one patient. Botulinum Toxin Type A is a category of medicine to correct light folds and shrink the expression.
This product is a hygienic, lyophilized form of purified botulinum toxin type A, produced from the unfinished toxin of the culture of the Hall strain of Clostridium botulinum developed in a medium holding trypticase and yeast extract. A series of cleansing procedure were taken to form a crystal clear complex consisting of the active high molecular weight toxin protein as well as an allied hemagglutinin. After re-diluted and dialyzed the clear toxin, an accurate volume of the sterilized clarified (0.2 microns) toxin were added to a solution having gelatin-dextran-sucrose, and then lyophilized. Each vial of BTXA has 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.

INDICATIONS:
This medication is administrated for the treatment of blepharospasm, hemi facial tremor in adults also some kinds of strabismus, particularly for important paralytic strabismus, comitant strabismus, strabismus caused by endocrine myopathy and strabismus which cannot be amended through operation. Anti-Wrinkle, Thin expressions and legs.

USAGE AND DOSE:
1. Place for injection:
- For blepharospasm: the injection should be used intramuscularly at some points of upper also inferior covers, i.e., using 4 to 5 places of injection into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial tremor: besides the locations mentioned above, three other places on middle, lower face also cheek should be inoculated intramuscularly. BTXA can be used at the locations of two sides of eyebrow, upper lip or the lower jaw according to the diseases.
- For strabismus: the BTXA (Botulinum Toxin Type A for Therapy) is inoculated using a coaxial electrode needle with electromyography guidance or amplifier under topical anesthesia of 0.5% Decarine. The inoculations into additional ocular muscles are selected according to the type and position of strabismus.

2. Measure:
150 IU have to be watering into 2.0-2.5ml sterilized water before usage.
Dissolve with sterile normal saline according to different requests before injecting. The white loose product changes to be neutral or yellowish clear solution after the watering.
- For blepharopasm and hemi facial spasm: the injection may be indicated following above advices. The first measure of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. If the primary treatment is considered insufficient 1 week later, an additional injection can be indicated. Dual dose of 5 U / 0.1 ml could be indicated to recrudescent persons. But the limitation of total dosing of 55 U for one insertion and 200 U for 1 month should not be exceeded.
- For strabismus: for vertical as well horizontal muscle strabismus of less than 20 prism diopters, the first dose into every muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the initial dose into each muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the first dose into every muscle is 2.5 U also may be increase (to 5.0 each time) depending on the response; for persistent VI cranial nerve paralysis continued for more than one month. The inserting volume into ever muscle should not more 0.1 ml. To persons, taking insufficient reply, extra insertion may be given. To recrudescent persons, the dosing could be repeated or increased irregularly. But for every muscle the extreme dose must be less than 5 U / inj.

The Watering of BTXA (Botulinum Toxin Type A for Therapy):
The watering of this product with sterile normal saline must be done carefully on the basis of real requirements. Following is a reference table of dilution to be suggested. The vial must be trembling quetly once adding sterile normal saline to the whole watering. The dissolving BTXA (Botulinum Toxin Type A for Therapy) should be used at once or maintained in refrigerator at 2-8 degrees as well to be injected within 4 hours. The bottle also the needle used with this preparation as well as the lasting BTXA solution has to be prepared after purification.

UNEXPECTED RESULTS:
Passing ptosis of the eyelid, weakness of the minor eyelid, reduced blinking, eyelid close moderately, weakness of facial muscles, etc. may happen to a number of persons who take this medication healing for blepharospasm as well hemi facial contraction. But, all the symptoms will go without any remedy within 3 to 8 weeks. Momentary and diverse point of ptosis of the eyelid, vertical deviance as well rarely mydriasis, which connected to the distribution of the toxin to the muscles adjacent, can happen to some persons who used this product healing for strabismus. The symptoms will disappear without any therapy within a few weeks.

CONTRAINDICATIONS:
BTXA is not suggested in individuals with anaphylactic structure and identified reaction to this medication.

PRECAUTIONS:
The injection technique must be suggested later to patients who have fever, acute infectious illness also prudently to the patients with heart, liver, lung troubles, active tuberculosis, blood problems as well pregnant women.
Botulinum toxin could be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of products must not be used during the injecting of BTXA (Botulinum Toxin Type A for Therapy).
BTXA (Botulinum Toxin Type A for Therapy) is in minim result or without any result to the people in the following situations: strabismus above 50 prism diopters, fixed strabismus, strabismus initiated by extremely corrected surgery, chronic paralysis strabismus, and chronic VI or III cranial nerve paralysis, severe muscle fiber contracture.
1:1000 adrenalines have to be prepared in case of occasional accident.

SHELF LIFE:
3 years from the date of lyophilization. The result is clear and may be last 6 months.

STORAGE:
Store at a temperature of -5 to -20 gr C (23 to -4 gr F). Keep new vial at -5 temperatures.

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